Publications

Research Articles & Reviews Published

(in reverse chronological order)

1. Christoforidou, E., Moody, L., Joilin, G., Simoes, F.A., Gordon, D., Talbot, K., Hafezparast, M. (2023). The ALS-associated TDP-43M337V mutation dysregulates microglia-derived extracellular microRNAs in a sex-specific manner. BioRχiv.

2. Christoforidou, E., Simoes, F.A., Gordon, D., Talbot, K., Hafezparast, M. (2023). Aberrant dynein function promotes TDP-43 aggregation and upregulation of p62 in male mice harboring transgenic human TDP-43. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration.

3. Christoforidou, E., Joilin, G. & Hafezparast, M. (2020). Potential of activated microglia as a source of dysregulated extracellular microRNAs contributing to neurodegeneration in amyotrophic lateral sclerosis. Journal of Neuroinflammation, 17, 135.

4. McDonald, M., Christoforidou, E., Van Rijsbergen, N., Gajwani, R., Gross, J., Gumley, A.I., Lawrie, S.M., Schwannauer, M., Schultze-Lutter, F., Uhlhaas, P.J. (2018). Using Online Screening in the General Population to Detect Participants at Clinical High-Risk for Psychosis. Schizophrenia Bulletin, 45(3), pp. 600–609.

Articles Submitted

5. ᵃSimoes, F.A., ᵃChristoforidou, E., Raphaelle, C., Dupuis, L., Hafezparast, M. Dose-Dependent Dynein Reduction in Male Mice Induces ALS-Like Motor Dysfunction with Neuromuscular Junction and Motor Neuron Pathology. ᵃco-first authors

Articles In Preparation

6. Moody, L., Christoforidou, E., Joilin, G., Newbury, S., Leigh, N., Mullen, L., Hafezparast, M. The role of dysregulated SOD1(G93A) microglia-released microRNAs in ALS pathology.

7. ᵃChristoforidou, E., ᵃSimoes, F.A., Joilin, G., Hafezparast, M., et al. Loss-of-Function Mutation in TDP-43 Leads to Altered Expression and Splicing of Neuromuscular-Associated Genes in Lumbar Spinal Cord. ᵃco-first authors

Open-Access Code & Software

8. Christoforidou, E. (2023). Long-read RNA-seq Plotting Suite: A Collection of MATLAB Functions for Data Processing, Visualization, and Analysis of Long-read RNA Sequencing Data. Zenodo.

9. Christoforidou, E. (2023). COVID-19 Global Data Visualisation: A MATLAB GUI Application. Zenodo.

10. Christoforidou, E., Simoes, F.A. & Hafezparast, M. (2022). NMJ-MN Image Analysis Toolkit: A Comprehensive Tool for Morphometric and Protein Distribution Analysis of Neuromuscular Junction and Motor Neuron Microscopy Images. Zenodo.

11. Christoforidou, E. & Hafezparast, M. (2022). Cell Morphometry: MATLAB Functions for Analysis of Microscopy Images. Zenodo.

Publicly Available Datasets

12. RNA Sequencing Data for Study of Microglia-derived MicroRNA.
    • Repository: European Nucleotide Archive (ENA)
    • Accession number: PRJEB61796
    • Date: 2024
    • Associated publication: Christoforidou, E., Moody, L., Joilin, G., Simoes, F.A., Gordon, D., Talbot, K., Hafezparast, M. The ALS-associated TARDBP-M337V mutation dysregulates microglia-derived extracellular microRNAs in a sex-specific manner.
    • Brief Description: This dataset includes RNA sequencing data from a study investigating sex-specific, genotype-specific, and context-specific microRNA release from microglia.

Other

13. Christoforidou, E. (2022). Investigating the contributions of impaired cytoplasmic dynein 1, TDP-43, and microglia-derived microRNA to the pathology of amyotrophic lateral sclerosis (PhD Thesis, embargoed until 7 February 2025). University of Sussex, Brighton.

My CRediT contributions:

(Associated with numbered articles above)

1. Methodology, Software, Validation, Formal analysis, Investigation, Data Curation, Writing - Original Draft, Writing - Review & Editing, Visualization.

2. Software, Formal analysis, Investigation, Data Curation, Writing - Original Draft, Writing - Review & Editing, Visualization.

3. Writing - Original Draft, Writing - Review & Editing, Investigation.

4. Investigation, Data Curation, Visualization.

5. Methodology, Software, Validation, Formal analysis, Investigation, Data Curation, Writing - Review & Editing, Visualization.

6. Methodology, Writing - Review & Editing.

7. Methodology, Software, Validation, Formal analysis, Investigation, Data Curation, Writing - Original Draft, Writing - Review & Editing, Visualization.

8. Software.

9. Software.

10. Methodology, Software.

11. Methodology, Software.