Publications

Research Articles & Reviews Published

(reverse chronological order)

1. Christoforidou, E., Simoes, F.A., Gordon, D., Talbot, K., Hafezparast, M. (2023). Aberrant dynein function promotes TDP-43 aggregation and upregulation of p62 in male mice harboring transgenic human TDP-43. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration.

   • My CRediT contributions: Software, Formal analysis, Investigation, Data Curation, Writing - Original Draft, Writing - Review & Editing, Visualization.

2. Christoforidou, E., Joilin, G. & Hafezparast, M. (2020). Potential of activated microglia as a source of dysregulated extracellular microRNAs contributing to neurodegeneration in amyotrophic lateral sclerosis. Journal of Neuroinflammation, 17, 135.

   • My CRediT contributions: Writing - Original Draft, Writing - Review & Editing, Investigation.

3. McDonald, M., Christoforidou, E., Van Rijsbergen, N., Gajwani, R., Gross, J., Gumley, A.I., Lawrie, S.M., Schwannauer, M., Schultze-Lutter, F., Uhlhaas, P.J. (2018). Using Online Screening in the General Population to Detect Participants at Clinical High-Risk for Psychosis. Schizophrenia Bulletin, 45(3), pp. 600–609.

   • My CRediT contributions: Investigation, Data Curation, Visualization.

Articles In Preparation or Nearing Submission

1. Christoforidou, E., Moody, L., Joilin, G., Simoes, F.A., Gordon, D., Talbot, K., Hafezparast, M. The ALS-associated TARDBP-M337V mutation dysregulates microglia-derived extracellular microRNAs in a sex-specific manner.

   • My CRediT contributions: Methodology, Software, Validation, Formal analysis, Investigation, Data Curation, Writing - Original Draft, Writing - Review & Editing, Visualization.

2. Moody, L., Christoforidou, E., Joilin, G., Newbury, S., Leigh, N., Mullen, L., Hafezparast, M. The role of dysregulated SOD1(G93A) microglia-released microRNAs in ALS pathology.

   • My CRediT contributions: Methodology, Writing - Review & Editing.

3. ᵃSimoes, F.A., ᵃChristoforidou, E., Raphaelle, C., Dupuis, L., Hafezparast, M. RDose-dependent reduction of cytoplasmic dynein function in male mice triggers motor dysfunction with ALS-Like motor neuron and neuromuscular junction pathology. ᵃco-first authors

   • My CRediT contributions: Methodology, Software, Validation, Formal analysis, Investigation, Data Curation, Writing - Review & Editing, Visualization.

4. ᵃChristoforidou, E., ᵃSimoes, F.A., Joilin, G., Hafezparast, M., et al. Loss-of-Function Mutation in TDP-43 Leads to Altered Expression and Splicing of Neuromuscular-Associated Genes in Lumbar Spinal Cord. ᵃco-first authors

   • My CRediT contributions: Methodology, Software, Validation, Formal analysis, Investigation, Data Curation, Writing - Original Draft, Writing - Review & Editing, Visualization.

Open-Access Code & Software

1. Christoforidou, E. (2023). Long-read RNA-seq Plotting Suite: A Collection of MATLAB Functions for Data Processing, Visualization, and Analysis of Long-read RNA Sequencing Data. Zenodo.

   • My CRediT contributions: Software.

2. Christoforidou, E. (2023). COVID-19 Global Data Visualisation: A MATLAB GUI Application. Zenodo.

   • My CRediT contributions: Software.

3. Christoforidou, E., Simoes, F.A. & Hafezparast, M. (2022). NMJ-MN Image Analysis Toolkit: A Comprehensive Tool for Morphometric and Protein Distribution Analysis of Neuromuscular Junction and Motor Neuron Microscopy Images. Zenodo.

   • My CRediT contributions: Methodology, Software.

4. Christoforidou, E. & Hafezparast, M. (2022). Cell Morphometry: MATLAB Functions for Analysis of Microscopy Images. Zenodo.

   • My CRediT contributions: Methodology, Software.

Publicly Available Datasets

1. RNA Sequencing Data for Study of Microglia-derived MicroRNA.
   • Repository: European Nucleotide Archive (ENA)
   • Accession number: PRJEB61796
   • Date: (embargoed until publication of the associated article)
   • Associated publication (awaiting internal review): Christoforidou, E., Moody, L., Joilin, G., Simoes, F.A., Gordon, D., Talbot, K., Hafezparast, M. The ALS-associated TARDBP-M337V mutation dysregulates microglia-derived extracellular microRNAs in a sex-specific manner.
   • Brief Description: This dataset includes RNA sequencing data from a study investigating sex-specific, genotype-specific, and context-specific microRNA release from microglia.

Other

1. Christoforidou, E. (2022). Investigating the contributions of impaired cytoplasmic dynein 1, TDP-43, and microglia-derived microRNA to the pathology of amyotrophic lateral sclerosis (PhD Thesis, embargoed until 7 February 2025). University of Sussex, Brighton.