Research Experience

Research Projects

  • Sep 2021 - Sep 2022 (1 year, 1 month)

    • Project title: "Investigating the link between dynein function, TDP-43 aggregation, and autophagy in ALS"
    • Location: University of Sussex
  • Dec 2020 - Aug 2022 (1 year, 9 months)

    • Project title: "The effect of cytoplasmic dynein 1 dysfunction on neuromuscular junctions and protein aggregation in motor neurons"
    • Location: University of Sussex
  • May 2020 – May 2023 (3 years)

    • Project title: "An exploratory analysis of the transcriptomic profile and alternative splicing of a TDP-43 mutant"
    • Location: University of Sussex
  • May 2020 – Aug 2022 (2 years, 3 months)

    • Project title: "The role of cytoplasmic dynein 1 in the microglial response to lipopolysaccharide"
    • Location: University of Sussex
  • Aug 2019 – Feb 2023 (3 years, 6 months)

    • Project title: "The effect of an ALS-linked TARDBP mutation on extracellular miRNAs from microglia"
    • Location: University of Sussex
  • Apr 2019 – Jul 2019 (4 months)

    • Project title: "Imaging spontaneous calcium activity in the white matter"
    • Location: University of Sussex
    • Techniques used:
      • Cranial window surgery
      • Implantation of a cannula in the brain
      • Two-photon imaging in vivo
  • Jan 2019 – Mar 2019 (3 months)

    • Project title: "Potential of inflammatory microglia as a source of extracellular microRNAs in amyotrophic lateral sclerosis"
    • Location: University of Sussex
  • Sep 2018 – Dec 2018 (4 months)

    • Project title: "Investigating the effects of a synaptically-enriched glutamate reporter on basal AMPAR-mediated synaptic transmission"
    • Location: University of Sussex
    • Techniques used:
      • Whole-cell patch-clamp electrophysiology
      • Primary neuronal culture
      • Viral transduction
      • Programming
  • Jan 2018 – Apr 2018 (4 months)

    • Project title: "Investigating the effects of intravenous catecholamines on heart rate and blood pressure under inhalational anaesthesia"
    • Location: University of Glasgow
    • Techniques used:
      • Inducing and maintaining general inhalational anaesthesia
      • Tracheostomy
      • Arterial and venous cannulation
      • Intravenous injections
      • Exposure and electrical stimulation of the cervical vagus nerve
  • Sep 2017 – Dec 2017 (4 months)

    • Project title: "Investigating the therapeutic potential of angiotensin-(1-7) in a hypertensive model of stroke"
    • Location: University of Glasgow
    • Techniques used:
      • Histology
      • Analysis of MRI images